Alzheimer's Speaks Radio Hurukuro MemTrax: Kuwana Wega neDementia - Chikamu 2
Svondo rapfuura, mune yedu Blog positi, takatanga hurukuro yedu yeAlzheimer's Speaks Radio nesumo kuna Dr. Ashford, muvambi we MemTrax bvunzo, uye mhedziso yaLori La Bey uye nhoroondo yake yekubata neDementia. Vhiki rino Dr. Ashford neni tinokurukura Sekuru vedu vaiva nehosha ye<em>Alzheimer uye tinovaudza zvazvaiva zvakaita kuva nechirwere ichi chinoparadza. Vhiki rino tichanyora mamwe ebvunzurudzo uye nekupa ruzivo runobatsira kubatsira kusimudzira tsvakiridzo yechirwere cheAlzheimer uye kuziva.
Chikamu 2: Kuongorora iyo MemTrax Muedzo uye Kuwanda kweDementia
Lori:
Tisati tapinda mumutsara wedu wekubvunza ndinodawo kusuma Curtis Ashford, wandinotenda kuti mwanakomana wako, uye akatanga kufarira kuongororwa kwenjere semudzidzi paCalifornia State University kuSan Jose (Silicon Valley) kwaakapedza kudzidza muna 2011. Mumakore matatu apfuura akashanda padhuze kuti agadzirise ichi chiri nyore chekuongorora chiitiko chekuongorora shanduko mundangariro vachishandisa social media, komputa, uye internet tekinoroji kuzivisa uye kukurudzira kakawanda uye kunoenderana ndangariro kuongorora. Curtis ane shungu nekusimudzira kukasika kuonekwa kwekuchinja kwendangariro kunogona kuratidza kutanga kwechirwere cheAlzheimer kana kuvapo kwezvimwe zvikonzero zvekusaziva. Parizvino ari kutungamira MemTrax mukugadzira iyo Kuongorora kweKuongorora software ine sensitivity yekuongorora yekutanga kwekutanga kwekuchinja kwendangariro uye kukurudzira kupindira kwekutanga kusati kwaita hurema hwekuvandudza kwekuziva. Saka titambire Curtis, uri sei nhasi?
Curtis:
Mhoro Lori, ndinokutendai zvikuru nekuva nesu nhasi!
Lori:
Hameno ndiri kufara hangu, ndanzwa nezvekambani yenyu kwerinenge gore zvino uye chimwe chezvandiri kuda kukubvunzai mese ndichatanga naCurtis pano. Wakambobatwa here iwe pachako mumhuri yako kana shamwari yepedyo ine dementia, vateereri vedu vanogara vachifarira kunzwa kana paine pachedu.
Curtis:
Hongu, sekuru vangu chaizvo, sekuru vangu John vaive nazvo zvakanyanya. Ndakanga ndiri muduku zvikuru, anenge makore 14 kana kuti 15, sezvaakavamba kushata. Ndaiti ndichitandara naye, zvaisiririsa nekuti pese pawaidzokera kushanya aitokanganwa zvimwe nezvako kana baba vangu kana kukanganwa zita remumwe munhu. Iwe unogona zvechokwadi kuitora nguva imwe neimwe uye iwe unoziva kuti chimwe chinhu chiri kuitika.
Lori:
Mmm, hongu. Dr. Ashford, ko imi, ndibaba venyu vaiva nedementia kana kuti ndiro rimwe divi?
Dr. Ashford:
Aiwa vaiva baba vangu.
Kufarira kwangu mune izvi kwakabva kune imwe nzira, pandakanga ndiri kuBerkeley kufarira kwangu kunze kwezvematongerwe enyika kwakanga kuri kuedza kurarama nokusingaperi saka ndaifarira zvikuru kukwegura, uye kuti ndingaimisa sei. Sezvandairamba ndichiidzidza ndakatanga kutarira uropi senhengo huru inodzora zvinhu zvose, uye ndakafunga kuti kana ndaizonzwisisa kukwegura ndaizofanira kunzwisisa kuti uropi hunodzora sei kukwegura. Nokufamba kwenguva ndakaona kuti ndaisazokwanisa kumisa kuchembera, ndaingofanira kurarama upenyu hwakanakisisa hwandaigona. Ndakanga ndichiri kufarira nzira dzekuchembera uye zvakazoitika kuti sezvandakatarisa pahuwandu hwevanhu uye vana vanoputika, izvo zvandiri nhengo yavo, kukwegura, pane zvinhu zvakawanda zvataigona kuita kudzivirira kufa; kusaputa midzanga, kurarama hupenyu hune hutano, kupfeka mabhandi ezvigaro zvedu, uye kutiza matambudziko mazhinji angaita kuti ufe. Asi zvakazoitika, pandakawedzera kudzidza zvinhu, chinetso chakakomba chandakaona ndichitarisira chaiva chirwere cheAlzheimer, uye sezvo vana vanokura vachikura uye vanozvitarisira zviri nani uye kurarama kwenguva yakareba uye kwenguva refu dambudziko reAlzheimer's richava dambudziko rinoparadza zvakanyanya muzana remakore.
Saka ndakafarira chirwere cheAlzheimer kubva paPublic Health maonero. Muna 1978, ndini ndakava mukuru mukuru mugari wepachipatara chevarwere vepfungwa kuUCLA uye ndakatanga kuona kuti vangangosvika 2 pavarwere vashanu voga voga vatakabvuma kuti hapana chavanorangarira. Ndaivakumbira kuti vayeuke mazwi mashanu uye zviri pachena kuti chero munhu aigona kuyeuka aya mazwi akareruka, ndaidzoka ndotaura kuti ndeapi mazwi andakakukumbira kuti uyeuke? Ipapo vanhu 5 pavashanu voga voga vaisatomboyeuka kuti ndakavakumbira kuyeuka mashoko mashanu, uye ndakaita sekuti, “izvi hazvina musoro.” Ndakanga ndave ndichifarira zvikuru ndangariro nechekare, muperekedzi wangu akanga ari Purofesa Lissy Jarvik, akanga achifunda hosha yeAlzheimer. Saka takafunga nezvedambudziko. Zviripachena isu taifunga kuti chirwere cheAlzheimer chaive chakajairika kupfuura chero munhu angaziva, uye zvirinani titange kufarira zvatinofanira kuita nezvazvo. Takadzidza zvimwe zvekutanga zvakawanikwa nesainzi zvakange zvichangobva kubuda izvo zvakaratidza maitiro chaiwo muuropi akange abatwa nechirwere cheAlzheimer chaisanganisira kemikari inonzi Acetyl-choline. Saka takafunga nzira yekuedza kuwedzera huwandu hweAcetyl-choline muuropi uye izvo zvinotitungamira kushandisa mushonga unonzi physostigmine uri mushonga wakafanana nemishonga yemazuva ano inoshandiswa kurapa chirwere cheAlzheimer, senge donepezil (Aricept) kana galantamine ( Razadyne), kana rivastigmine (Excelon uye Excelon chigamba). Basa iroro takariita muna 5-2 tikariburitsa muna 5 saka ndiyo yaive pfungwa yekuedza kurapa varwere vane chirwere ichi, uye pakange paine kufanana kwekushandisa mushonga uyu neunoshandiswa paParkinson.
Chandakakurumidza kuziva ndechokuti mishonga iyi haimise hosha yeAlzheimer inoita seinoibatsira zvishoma, asi hairegi. Isu tinofanirwa kunyatsonzwisisa chirwere ichi kuti tigone kumisa maitiro echirwere zvachose, uye ndichiri kutenda kuti zvinogoneka, uye kana tikaenda pasi negwara rekutsvaga ndinotenda kuti tinogona kubvisa chirwere cheAlzheimer zvachose, asi zvichatora kunzwisisa. kuti hurongwa hwacho chii. Ndipo pandakaenda mukugadzira dzidziso yeurouroplasticity uye kuti neuroplasticity ndiyo inorwiswa muuropi neAlzheimer pathology. Paingova nebepa rakabuda muJournal rainzi "Kuchembera," Gunyana 2014, neimwe yeshamwari dzangu, Dale Bredesen, anomhanyisa Buck Institute on Aging muNorthern California, uye ane bepa rakanzi "Reversal of Cognitive Decline. , A Novel Therapeutic Programme,” uye ari kushandisa dzidziso yandakanga ndagadzira kare muna 2002, yekuti kana ukanzwisisa nzira chaidzo dzinoshandiswa neAlzheimer's kurwisa uropi unogona kushandura zvinhu zvakawanda zvakasiyana mukudya kwako uye zvakatipoteredza zvinogona kumira. nzira iyi zvachose. Izvi ndizvo chaizvo zvatinoda kuita, hatidi kuti vanhu varapwe chirwere cheAlzheimer, tinoda kuti chidzivirirwe. Ndiri kufara kutaura newe zvakawanda pamusoro pazvo.
Lori:
Ndizvozvo. Zvakanaka, izvo zvinoshamisa, ndinoziva kuti Alzheimer's Disease International ichangobuda neshumo hombe pamusoro pekudzikisa njodzi yandinoziva Mart Wortman, Executive director, akanyatso kutaura kuti iyi yanga isiri vimbiso. Iwe unoziva zvese zvezvinhu izvi zvavari kutaura zvakangonakira muviri wedu sewese asi zvine chokwadi sekuti heck haigone kukuvadza kuve wakanyanya kuita maererano nekufambisa zvinhu kumberi.