Kutendeseka kweMemTrax Chiyeuchidzo Bvunzo Kuenzaniswa ne Kuongorora kweMontreal Kuziva muKuonekwa kweMild Cognitive Impairment uye Dementia nekuda kwechirwere cheAlzheimer muChinese Cohort.

 

Xiaolei Liu, Xinjie Chen , Xianbo Zhou , Yajun Shang, Fan Xu , Junyan Zhang, Jingfang He, Feng Zhao, Bo Du, Xuan Wang, Qi Zhang, Weishan Zhang, Michael F Bergeron, Tao Ding, J Wesson Ashford, Lianmei Zhong

• PMID: 33646151
• DOI: 10.3233/JAD-200936

ngovepo

 

Background: Iyo inoshanda, yakavimbika, inowanikwa, inobata, uye inokwanisika yekuziva yedhijitari chidzitiro chiridzwa yekushandiswa kwekiriniki iri kudiwa nekukurumidza.

 

Chinangwa: To ongorora kushandiswa kwekiriniki kweMemTrax ndangariro bvunzo yekukurumidza kuona kwekukanganisa kwekuziva muchikwata cheChinese.

 

Nzira: Iyo 2.5-miniti MemTrax uye iyo Montreal Cognitive Assessment (MoCA) yakaitwa ne50 kiriniki yakaongororwa cognitively normal (CON), 50 mild cognitive impairment nekuda kweAD (MCI-AD), uye 50 Alzheimer's disease (AD) vanozvipira vatori vechikamu. Chikamu chemhinduro chaidzo (MTx-% C), nguva yekupindura inorehwa (MTx-RT), uye zvibodzwa zvakaumbwa (MTx-Cp) zveMemTrax uye zvibodzwa zveMoCA zvakaongororwa zvakaenzaniswa uye macurves eanogamuchira (ROC) akagadzirwa.

 

Results: Multivariate linear regression ongororo yakaratidza MTx-% C, MTx-Cp, uye MoCA mamakisi aive akadzikira zvakanyanya muMCI-AD maringe neCON uye muAD nemapoka eMCI-AD (ese aine p≤0.001). Pakusiyaniswa kweMCI-AD kubva kuCON, yakagadziridzwa MTx-% C cutoff ye81% yaive ne72% senitivity uye 84% chaiyo ine nzvimbo iri pasi pe curve (AUC) ye0.839, nepo MoCA mamakisi makumi maviri nematatu aive ne23% kunzwa. uye 54% chaiyo ine AUC ye86. Pakusiyaniswa kweAD kubva kuMCI-AD, MTx-Cp ye0.740 yaive ne43.0% senitivity uye 70% chaiyo ine AUC ye82, nepo MoCA mamakisi makumi maviri aive ne0.799% senitivity uye 20% chaiyo ine AUC ye84.

 

mhedziso: MemTrax inokwanisa kunyatsoona zvese zvakaongororwa nekiriniki MCI uye AD nekurongeka kuri nani kana zvichienzaniswa neMoCA yakavakirwa paAUCs muChinese cohort. Kutendeseka kweMemTrax Memory Test kwakagadzwa.

 

Keywords: Chirwere cheAlzheimer; chombo chekuongorora chekuziva; kuenderera mberi nekuzivikanwa basa paradigm; nyoro yekuziva kukanganisa.