Ndingacothisa njani ukukhula kwesifo sika-Alzheimer?

Kule veki siqhubeka nodliwano-ndlebe lwethu kunye noGqr. Ashford kwaye uchaza ukuba kutheni icandelo lophando lwe-Alzheimer lingakhange libe nemveliso kakhulu kwaye kutheni "likwindlela ephosakeleyo ngokupheleleyo." UGqr. Ashford ukwafuna ukukufundisa ngendlela yokuthintela isifo sika-Alzheimer kunye nesifo sengqondo esiyingozi. Isifo sengqondo esixhalabisayo sinokuthintelwa kwaye kungcono ukuba uqonde kwaye uphelise izinto ezinokuba yingozi onokuthi ujongene nazo. Funda njengoko siqhubeka nodliwano-ndlebe lwethu oluvela kwi-Alzheimer's Speaks Radio.

Lori :

UGqr. Ashford ungasichazela ubume besifo se-Alzheimer sangoku kunye nophando lwe-dementia phaya. Ndiyazi ukuba ubutshilo ukuba ubucinga ukuba siya kukwazi ukuyinqanda le nto hayi nje ukuyinyanga kodwa ukuyinqanda. Ingaba sikhona isifundo esinye okanye ezibini osonwabileyo eziqhubekayo phaya?

Uphando lwe-Alzheimer

UGqr. Ashford :

I-Aggravated lelona gama lilungileyo lemvakalelo yam malunga nophando lwe-Alzheimer. Bendikwintsimi ukusukela ngo-1978 kwaye bendinethemba lokuba siya kuba siyigqibile yonke le nto i-10 okanye i-15 kwiminyaka eyadlulayo. Sisajongene nayo. Kukho inqaku elalikuwo omabini indalo kwaye Inzululwazi yaseMelika, iimagazini ezihloniphekileyo kakhulu, ngoJuni ka-2014 ezazithetha malunga nalapho uphando lwaluhamba khona kwinkalo yesifo se-Alzheimer. Ukusukela ngo-1994 indawo yesifo i-Alzheimer ibilawulwa yinto ebizwa ngokuba yi-Beta-amyloid Hypothesis, ingcinga yokuba iBeta-amyloid ngunobangela wesifo i-Alzheimer's. Kwakukho ubungqina obuninzi obuqinileyo obubhekiselele kweli cala kodwa aluzange lubonise ukuba i-Beta-amyloid yayiyeyona nto ibangela unobangela, nangona kunjalo, intsimi yayilawulwa yile ngcamango yokukhangela indlela yokuthintela ukuphuhliswa kwe Beta-amyloid. Eyaziwa ngoku njengeprotheyini eqhelekileyo engqondweni, enye yezona proteni zijike kakhulu ebuchotsheni. Ukuzama ukuyiphelisa kuyafana nokuthi “Kulungile, kukho umntu owophayo. Masisuse athwala ezinokunqanda ukopha.” Ibilulwalathiso olulahlekisa ngokupheleleyo. Malunga nexesha elinye ebutsheni beminyaka yee-1990 kwafunyaniswa ukuba kukho umba wemfuza onxulumene nesifo sika-Alzheimer, ngoku akukho mntu uthanda ukujongana nemizila yemfuza ingakumbi ukuba iza kubaxelela ukuba maninzi amathuba okuba bangenwe sisifo sika-Alzheimer. Kukho ujini olwafunyanwa kwiminyaka engama-20 eyadlulayo ebizwa I-Apolipoprotein E (APOE), kwaye ndiyathemba ukuba intsimi iya kubuya ekuqondeni i-APOE gene kunye nento eyenzayo.

Umba kukuba iprotein ye-Amyloid yangaphambili iya kumacala amabini ahlukeneyo inokuthi ihambe yenze ii-synapses ezintsha, eziluqhagamshelo kwingqondo, okanye ukuphelisa i-synapses. Oku kulungile kwimigca yento esandula ukuphumelela ibhaso leNobel namhlanje ukuba kukho iplastiki eqhubekayo kunye nokutshintsha rhoqo uxhulumaniso engqondweni ukuba i-Alzheimer ihlasela. Ukuba siyayiqonda loo nto kunye nendlela i-genetic factor ehambelana nolo hlaselo ndicinga ukuba siya kukwazi ukuphelisa isifo se-Alzheimer. Inqaku likaGqr Bredesen kwi Ukuguga dwelisa malunga ne-30 yezinto ezahlukeneyo ezazibalulekile kwisifo sika-Alzheimer kwaye ezi luhlobo lwezinto ekufuneka sizijonge ukuze sibone zonke izinto ezahlukeneyo esinokuzenza ukuthintela isifo sika-Alzheimer. Makhe ndikunike umzekelo ube mnye: Akukacaci ukuba isifo seswekile sinxulumene nesifo sika-Alzheimer kodwa sinxulumene nesifo sengqondo esiyingozi, sibangela isifo semithambo kunye ne-stroke esisisifo sesibini esikhokelayo esibangela ukuphambana kwengqondo. Nakweyiphi na imeko ufuna ukuthintela isifo seswekile kwaye olu hlobo lwesifo seswekile lwe-II luyathintelwa ngokwenza izinto ezinzima kakhulu njengokwenza umthambo owaneleyo, ukungatyebi kakhulu, nokutya ukutya okulungileyo. Zisuka nje ezo ziya kuba zezona zinto zilungileyo ekufuneka ziqwalaselwe ekuthinteleni isifo sika-Alzheimer okanye ubuncinci ukuphambana kwengqondo.

Indlela yokuThintela isifo sika-Alzheimer

Yitya ukutya okunesondlo, yenza umthambo owaneleyo, qiniseka ukuba awuwatyi isikali kwicala elingalunganga. Enye into ebalulekileyo esiyibonileyo kukuba abantu abanemfundo eninzi banesifo sika-Alzheimer esincinci, sinomdla kakhulu ekukhuthazeni abantu ukuba bafumane imfundo efanelekileyo kwaye baqhubeke nokufunda ubomi obude, ezo zizinto ezilula kakhulu. Unokungena kwezinye izinto ezifana nokulawula uxinzelelo lwegazi, ukubona ugqirha wakho rhoqo, ukubukela i-vitamin b12 kunye ne-vitamin D kuye kwabaluleke kakhulu. Kukho uluhlu olupheleleyo lwezinto ezinje, kuya kuba kubaluleke ngakumbi ukuba abantu baqaphele ezi zinto ukuthintela izinto ezithile zomngcipheko. Enye yezona zinto ziyingozi kakhulu kwisifo sika-Alzheimer kukwenzakala kwentloko. Nxiba ibhanti lesihlalo sakho xa ukhwele kwimoto yakho, ukuba uza kukhwela ibhayisekile, oko kulunge kakhulu kuwe, nxiba isigcina-ntloko xa ukhwele ibhayisekile yakho! Kukho iintlobo ngeentlobo zezinto ezilula esinokuthi, njengoko sinokuzilinganisa ngakumbi nangakumbi, sifundise abantu ukuba benze ntoni. Kuye kwavela ukuba kukho ubungqina obutsha nje obubonisa ukuba iziganeko ze-Alzheimer's ziyehla njengoko abantu belandela ezi ngcebiso zempilo zilungileyo kodwa kufuneka ukuba siwe phantsi ngokuthi wonke umntu alandele ezi ngcebiso zempilo zilungileyo.

UGqr. Ashford ucebisa ukuba uthathe I-MemTrax kanye ngeveki okanye kanye ngenyanga ukuze ufumane ukuqonda ngokubanzi ngempilo yobuchopho bakho. Thatha i Uvavanyo lwememori yeMemTrax ukuchonga iimpawu zokuqala ezinokubakho zokulahleka kwenkumbulo edla ngokunxulunyaniswa nayo Isifo se-Alzheimer.