Iyingozi kangakanani i-sodium valproate kubasetyhini abakhulelweyo?
Isodium valproate liyeza elixhaphakileyo kwaye lidla ngokusebenza kakhulu ukunyanga isifo sokuxhuzula. Nangona ngokuqhelekileyo kuthathwa njengekhuselekile kumntu othatha iyeza, i-valproate ye-sodium inokubeka ingozi enkulu kubantwana abangekazalwa ukuba umama wabo uthatha iyeza ngexesha lokukhulelwa.
Kufunyaniswe ukuba iziphene zokuzalwa ngokwasemzimbeni zifikelela kumaxesha angama-5 ngaphezulu kwabasetyhini abathatha i-valproate ye-sodium ngelixa bekhulelwe, echaphazela ngeenxa zonke. Iintsana ezi-1 kwabali-10. Okwangoku, ngeenxa zonke 4 kwi-10 abantwana unina wathatha ichiza ngexesha lokukhulelwa amava iingxaki zophuhliso.
Imingcipheko mikhulu kangangokuba i Iziko leSizwe lokuGqwesa kwezeMpilo kunye noNonophelo (NICE) incoma i-valproate ye-sodium akufanele isetyenziswe ekukhulelweni ngaphandle kokuba akukho ndlela yimbi kwaye, ukuba kufuneka isetyenziswe, i-dose ephantsi kakhulu kufuneka imiselwe. Nangona kunjalo, kusekho umngcipheko omkhulu emntwaneni kwaye oomama kuya kufuneka basayine iPhepha lokuVumela uMngcipheko.
Ziziphi iimpembelelo zesodium valproate kubantwana abangekazalwa?
Iziphumo ezichanekileyo ze-sodium valproate kumntwana ongekazalwa zinokuhluka kakhulu ukusuka kwimeko ukuya kwimeko. Zonke ziyimiba yobomi ngokubanzi engenako ukunyangeka kodwa inokupheliswa ngonyango olululo. Abantwana abachatshazelwa yile miba ke ngoko baya kufuna ukhathalelo olukhethekileyo kunye nenkxaso, amaxesha amaninzi ubomi babo bonke.
Iziphene zokuzalwa ezinxulumene nokusetyenziswa kwe-sodium valproate ngexesha lokukhulelwa ziquka:
- I-Spina bifida (apho intambo yomgogodla ihluleka ukuphuhlisa ngokufanelekileyo, ibangela imiba efana nokukhubazeka, ubuthathaka bemisipha kunye nokungazinzi)
- Iingxaki zeentliziyo (okubangelwa kukungasebenzi kakuhle kwentliziyo)
- Umlebe ocandekileyo / inkalakahla ecandekileyo (ifuna utyando olulungisayo)
- Uphawu lobuso (ezifana nempumlo encinci ejikisiweyo kunye nokugoba kwe-epicanthic)
- Imiba yamathambo (kubandakanya ukufinyela kwamalungu amancinci, iminwe emide ewelanayo kunye neenyawo ezikhubazekileyo)
- Imiba yesini (njengendlela yomchamo ephela kumzantsi welungu lobudoda)
Imiba yophuhliso enokubangelwa kukusetyenziswa kwechiza ngexesha lokukhulelwa ibandakanya:
- Ukulibaziseka ekufundeni ukuhamba
- Ukulibaziseka ekufundeni ukuthetha
- Intetho engafanelekanga nezakhono zolwimi
- Imiba yememori
- Ubukrelekrele obungaphantsi komndilili
Indlela yokwenza ibango lembuyekezo ngenxa yeziphene zokuzalwa ngenxa ye-valproate yesodium
Ukuba wena okanye umntwana wakho uneziphene zokuzalwa ngenxa yokusetyenziswa kwe-sodium valproate ngexesha lokukhulelwa, unokukwazi ukufaka ibango lembuyekezo. Oku kunokuba yimfuneko ukunceda ukujongana neziphumo zobomi bonke ze-Fetal Valproate Syndrome (FVS).
Ukuze wenze ibango, kuya kufuneka ukwazi ukubonisa ukuba akuzange ulunyukiswe ngokufanelekileyo ngeengozi ezinxulumene nechiza kwaye ezi ntlobo zamabango zinokuntsonkotha. Ngoko ke kucetyiswa ngamandla ukuba ufune iingcebiso zomthetho kubameli abanamava athile okuphatha amabango e-sodium valproate.
ABameli baMabango e-IBB ube namava kunye nezakhono zobuchwephesha ezifunekayo ukukunceda ufumane ukuhlaliswa kakuhle ngokukhawuleza nangokulula kangangoko. Kwiimeko ezininzi, imbuyekezo yeziphene zokuzalwa ezinxulumene ne-sodium valproate zinokukhuselwa ngaphandle kwenkundla, zenze izinto zibe lula kwaye zingabikho uxinzelelo kuwe. Amabango e-IBB anikezela ngothethwano lokuqala simahla kwaye akuphumeleli, akukho nkonzo yamabango ahlawulelwayo, ngoko ke akukho ndleko yangaphambili yokuqalisa ibango.