Alzheimer's Yana Magana Rediyo Tattaunawa MemTrax : Samun Keɓaɓɓen Tare da Dementia - Sashe na 2
Makon da ya gabata, a cikin mu blog Bayan haka, mun fara hirarmu ta Alzheimer's Speaks Radio tare da gabatarwa ga Dr. Ashford, wanda ya kirkiro na'urar. Gwajin MemTrax, da kuma bayyani na Lori La Bey da tarihinta na magance Dementia. A wannan makon ni da Dr. Ashford mun tattauna kan Kakanmu wanda ya kamu da cutar Alzheimer kuma mun raba abin da yake kama da samun mugunyar cutar. A wannan makon za mu rubuta ƙarin hirar da kuma ba da haske mai amfani don taimakawa haɓaka bincike da wayar da kan cutar Alzheimer.
Sashe na 2: Binciko Gwajin MemTrax da Yaɗuwar Hauka
Lori:
Kafin mu shiga cikin jerin tambayoyinmu ina so in gabatar da Curtis Ashford, wanda na yi imani danka ne, kuma ya ci gaba da sha'awar gwajin fahimta a matsayin dalibi a Jami'ar Jihar California a San Jose (Silicon Valley) inda ya kammala a 2011. A cikin shekaru 3 da suka gabata ya yi aiki tare don haɓaka wannan aikin dubawa mai sauƙi don tantance canje-canje a ƙwaƙwalwar ajiya ta amfani da kafofin watsa labarun, kwamfuta, da fasahar intanet don sanarwa da haɓaka ƙididdigar ƙwaƙwalwar ajiya akai-akai. Curtis yana da sha'awar inganta gano wuri na sauye-sauyen ƙwaƙwalwar ajiya wanda zai iya zama alamar farkon cutar Alzheimer ko kasancewar wasu abubuwan da ke haifar da rashin fahimta. A halin yanzu yana jagorantar MemTrax a cikin haɓaka kima na fahimi software tare da azanci don kimanta farkon farkon canje-canjen ƙwaƙwalwar ajiya da haɓaka sa baki da wuri kafin nakasa haɓakar fahimi ta haɓaka. To barka da warhaka Curtis, ya kake yau?
Curtis:
Hi Lori, na gode sosai don samun mu a yau!
Lori:
To kawai naji dadi, naji labarin kamfanin ku kusan shekara guda yanzu kuma daya daga cikin abubuwan da nake so in tambaye ku duka, zan fara da Curtis anan. Shin an taɓa ku da kanku a cikin danginku ko kuma aboki na kud da kud da ciwon hauka, masu sauraronmu koyaushe suna son su ji idan akwai ɗan sirri.
Curtis:
Haka ne, kakana a zahiri, kakana John yana da kyau mara kyau. Na kasance matashi, kusan 14 ko 15, yayin da ya fara lalacewa. Zan yi tafiya da shi, kuma abin baƙin ciki ne sosai domin duk lokacin da za ku koma ziyara yakan manta ɗan ƙaramin abu game da ku ko babana ko kuma ya manta sunan wani. Kuna iya ɗauka a kowane lokaci kuma ku san wani abu yana faruwa.
Lori:
Mhm, iya. Dr. Ashford, kai fa, mahaifinka ne ke da ciwon hauka ko kuma wancan bangaren?
Dokta Ashford:
A'a, mahaifina kenan.
Sha'awata ga wannan hakika ta fito ne daga wata hanya ta daban, lokacin da nake Berkeley sha'awata ban da duk siyasa tana ƙoƙarin rayuwa har abada don haka ina matukar sha'awar tsarin tsufa, da yadda zan dakatar da shi. Yayin da nake kara nazarinta sai na fara kallon kwakwalwa a matsayin babbar gabobin da ke sarrafa komai, sai na ga idan na fahimci tsarin tsufa sai na fahimci yadda kwakwalwa ke sarrafa tsufa. Yayin da lokaci ya wuce na gane ba zan iya dakatar da tsarin tsufa ba, kawai zan yi rayuwa mafi kyau da zan iya. Har yanzu ina sha'awar hanyoyin tsufa kuma ya zamana cewa yayin da na kalli yawan jama'a da jarirai, waɗanda ni mamba ne, suna girma, akwai abubuwa da yawa da za mu iya yi don hana mutuwa; ba shan taba sigari, rayuwa mafi koshin lafiya, sanya bel ɗin kujera, da kuma kubuta daga matsalolin da za su sa ku mutu. Amma sai ya zamana, lokacin da na kara nazarin al’amura, babbar matsalar da na ga ina sa rai ita ce cutar Alzheimer, kuma yayin da jarirai suka tsufa kuma suna kula da kansu sosai kuma suna rayuwa mai tsawo kuma matsalar cutar Alzheimer za ta kasance. mafi munin matsalar karni.
Don haka na sami sha'awar cutar Alzheimer ta fuskar Kiwon Lafiyar Jama'a. A cikin 1978, ni ne babban mazaunin farko a sashin kula da tabin hankali a UCLA kuma na fara ganin cewa kusan 2 daga cikin kowane marasa lafiya 5 da muka shigar ba za su iya tuna wani abu ba. Zan tambaye su su tuna kalmomi guda 5 kuma babu shakka kowa zai iya tunawa da waɗannan kalmomi masu sauƙi, zan dawo in ce menene kalmomin da na nemi ku tuna? Sannan 2 cikin kowane mutum 5 ba za su ma tuna cewa na tambaye su su tuna kalmomi 5 ba, kuma na kasance kamar, “wannan ba shi da ma’ana.” Na kasance mai sha'awar tunawa da gaske, mai ba ni shawara shine Farfesa Lissy Jarvik, wanda ya kasance yana nazarin cutar Alzheimer. Don haka muka yi tunanin matsalar. Babu shakka mun yi tunanin cutar Alzheimer ta fi kowa sani fiye da yadda kowa ya gane, kuma mu fara sha'awar abin da ya kamata mu yi game da shi. Mun yi nazarin wasu daga cikin binciken farko na kimiyya da suka fito da suka gano takamaiman hanyoyin da ke cikin kwakwalwa wadanda cutar Alzheimer ta shafa wadanda suka hada da wani sinadari mai suna Acetyl-choline. Don haka sai muka gano hanyar da za mu bi wajen kara yawan Acetyl-choline a cikin kwakwalwa kuma hakan ya sa mu yi amfani da wani magani mai suna physostigmine wanda wani magani ne mai kama da na yanzu da ake amfani da shi don magance cutar Alzheimer, kamar donepezil (Aricept) ko galantamine. Razadyne), ko rivastigmine (Excelon da Excelon patch). Mun yi wannan aikin a cikin 1978-1979 kuma mun buga shi a 1981 don haka shine ra'ayin ƙoƙarin jinyar marasa lafiya da cutar, kuma akwai kamanceceniya da amfani da wannan magani da waɗanda ake amfani da su na Parkinson.
Abin da na gane da sauri shi ne cewa waɗannan magungunan ba sa hana cutar Alzheimer kamar suna taimaka masa kaɗan, amma ba sa hana shi. Muna buƙatar fahimtar cutar da gaske don mu iya dakatar da tsarin cutar gaba ɗaya, kuma har yanzu na yi imani cewa hakan yana yiwuwa, kuma idan za mu gangara hanyar bincike daidai na yi imani za mu iya kawar da cutar Alzheimer gaba ɗaya, amma zai ɗauki ɗan fahimta. na menene tsari. Wannan shine lokacin da na shiga haɓaka ka'idar neuroplasticity da kuma yadda neuroplasticity shine abin da cutar Alzheimer ke kaiwa hari a cikin kwakwalwa. Akwai kawai wata takarda da ta fito a cikin Jarida mai suna "Tsafa," Satumba 2014, ta daya daga cikin abokaina, Dale Bredesen, wanda ke gudanar da Buck Institute on Aging a Arewacin California, kuma yana da takarda mai suna "Reversal of Cognitive Decline. , A Novel Therapeutic Program, "kuma yana amfani da wata ka'idar da na samo asali a cikin 2002, cewa idan kun fahimci ainihin hanyoyin da Alzheimer's ke kai hari ga kwakwalwa za ku iya canza abubuwa daban-daban a cikin abincinku da muhallin ku wanda zai iya tsayawa a zahiri. wannan tsari gaba daya. Wannan shi ne ainihin abin da muke so mu yi, ba ma so a yi wa mutane maganin cutar Alzheimer, muna so a hana shi. Na yi farin cikin yin magana da ku sosai game da hakan.
Lori:
Daidai To, wannan abin ban mamaki ne, na san cewa cutar Alzheimer ta International kawai ta fito da wani babban rahoto game da rage haɗarin da na sani Mart Wortman, Babban Darakta, ya keɓance cewa wannan ba garanti ba ne. Ka san duk waɗannan abubuwan da suke ambata suna da amfani ga jikinmu gaba ɗaya amma tabbas kamar yadda ba zai iya cutar da kasancewa mai himma wajen ciyar da abubuwa gaba ba.