"No laila, ma ke ʻano he maʻi ʻo Alzheimer kokoke loa i ka genetic akā ʻaʻole makemake ka poʻe e hana i kēlā."

I kēia pule ke nānā nui nei mākou nā genetics a me nā kumu pilikia o ka maʻi o Alzheimer. ʻAʻole makemake ka hapa nui o ka poʻe e ʻike inā he genetically predisposed lākou a no ke kumu maikaʻi, hiki ke makaʻu. Me ka ulu ʻana o kā mākou ʻano a ola lōʻihi, manaʻo wau e makemake ana ka poʻe e ʻike hou aʻe, ʻoiai mākou e ʻike ai i nā ala hou e pale ai i ka dementia a hoʻomaka e hana i kahi ala ʻoi aku ka wikiwiki i ko mākou olakino pilikino. ʻO ia ka mea e hoʻomau mau nei iaʻu i ka hoʻomohala ʻana MemTrax no ka neʻe ʻana i mua ma ke ʻano he poʻe pono mākou e hana i nā mea āpau e aʻo hou ai e pili ana i ko mākou kino a me ko mākou noʻonoʻo.

Mike McIntyre :

Manaʻo wau e nā kauka, ke lohe nei mākou e pili ana i kahi pilina genetic ma ʻaneʻi, ma ka liʻiliʻi loa he pilina ʻohana ma ka hihia o Joan akā ʻo Alzheimer mau ke ala ʻo Kauka Leverenz lāua ʻo Kauka Ashford? Loaʻa pinepine kahi ʻano genetic a i ʻole e hōʻoluʻolu i ka poʻe i kekahi manawa ke ʻōlelo lākou "ʻAʻole i loaʻa iaʻu kēia i loko o koʻu ʻohana, no laila ʻaʻole hiki iaʻu ke loaʻa."

Kauka Leverenz :

Manaʻo wau ua ʻike mākou ʻo ka makahiki ke kumu nui loa o ka pilikia no ka maʻi o Alzheimer. Aia nā ʻano genetic like ʻole, aia kekahi mau ʻohana kakaʻikahi kahi i hoʻoili maoli ai ʻoe i kahi mutation i loko o kahi moʻo e kumu ai ka maʻi a loaʻa iā ʻoe kahi pilikia 100% a hiki i kēlā poʻe ke hoʻomaka mua loa i ko lākou mau makahiki 30 a me 40 a ʻike ʻoe. he moʻolelo ʻohana ikaika no kēlā. Ke ʻike nei mākou aia kekahi mau kumu pilikia genetic i lawe ʻia e ka poʻe e like me ka Gene APOE e hoʻonui i kou pilikia akā ʻaʻole ia he manaʻo e loaʻa iā ʻoe no ka maopopo. Makemake nui mākou i kēlā mau mea pilikia. he aha kāna e haʻi mai ai iā mākou no ka maʻi. Manaʻo wau e ʻoi aku ka maikaʻi ma lalo o ka laina e haʻi mai kēia mau genes kumu pilikia iā mākou i ka pane ʻana o ka poʻe i ka lāʻau lapaʻau no laila makemake nui mākou i ka mālama ʻana i kēia mau mea i ko mākou hoʻomohala ʻana i nā lāʻau lapaʻau maikaʻi no Alzheimer.

Mike McIntyre :

ʻIke ʻoe iā Dr Ashford i ka nui o ka poʻe e makemake ana e nānā i ka poʻe hopohopo e pili ana i ka genetic component a me ke ʻano o ka ʻaha kūkā āu e hāʻawi ai?

Kauka Ashford :

Manaʻo wau ʻo kekahi o nā pilikia ʻaʻole ʻike ka poʻe i ke koʻikoʻi o ka genetic factor component. ʻO ka ʻokoʻa ma waena o nā kumu genetic i loaʻa i ka 30's 40's a me 50's a me nā mea e hiki mai ana ma hope, i ka wā e hiki mai ai ka maʻi ma hope, e like me nā wahine, ʻoi aku ka nui o kou make ʻana i kahi mea ʻē aʻe ʻoiai ua loaʻa iā ʻoe nā kumu pilikia genetic. . No laila, ma ke ʻano he kumu pilikia a ʻaʻole makemake ka poʻe e ʻike e pili ana i kā lākou mau pilikia. Aia kēia ʻano genetic a Dr. Leverenz i ʻōlelo ai, APOE, a aia ka 4 allele i ʻano kakaʻikahi akā ʻo ia ka mea nona ka 60% a i ʻole 70% o ka maʻi o Alzheimer. Aia kekahi kumu pilikia ma ka APOE 2 kahi inā loaʻa i nā kānaka he 2 kope o ia ʻano genetic hiki ke ola i 100 a ʻaʻole loaʻa ka maʻi Alzheimer. No laila, ma ke ʻano he ʻano genetic ka maʻi Alzheimer akā ʻaʻole makemake ka poʻe e hana i kēlā.

Aia kekahi mau kumu genetic lua ʻaʻole mākou i hoʻomaopopo maikaʻi i kēlā hopena inā e loaʻa iā ʻoe 5 mau makahiki ma mua o 5 mau makahiki ʻōpio ma muli o kāu kumu genetic. Ma mua o ka ʻoiaʻiʻo, aia kekahi mau mea pilikia ʻē aʻe akā manaʻo wau ʻaʻole mākou e paʻa i ka maʻi o Alzheimer a ʻaʻole mākou e pale a hiki i ka maopopo ʻana i ke ʻano o kēia APOE genetic factor a me nā mea ʻē aʻe e hoʻololi ai. ia. No laila he mea nui loa ka genetics iaʻu. ʻAʻole makemake ka poʻe e ʻike e pili ana iā ia.

Mike McIntyre :

Akā ʻaʻole ia he manaʻo ʻaʻole e loaʻa iā ʻoe ka Alzheimer inā ʻaʻole i loaʻa i kou mau mākua a i ʻole kou mau kūpuna? ʻO ʻoe paha ka mea mua?

Kauka Ashford :

ʻO kāna mau kumu genetic no laila ua lawe paha kou mau mākua i kekahi o nā genes a ua lawe paha nā mākua ʻelua i kekahi o nā genes APOE 4 a hiki iā ʻoe ke hoʻopau me 2 o lākou a ʻaʻole paha ʻoe i pau me kekahi o lākou. No laila pono ʻoe e ʻike i ke ʻano genetic kikoʻī, ʻaʻole wale ke ʻano o kāu moʻolelo ʻohana.

E kākoʻo i kā mākou mau hana a Alzheimer a hoʻokomo i ke olakino o kou lolo. E kākau inoa no kahi moʻokāki MemTrax a hāʻawi i kahi kumu maikaʻi. Manaʻo ʻo Kauka Ashford iā ʻoe e lawe i ka hoʻāʻo hoʻomanaʻo pūnaewele ma ka liʻiliʻi loa i hoʻokahi mahina akā hiki iā ʻoe ke lawe i nā hoʻokolohua hou i kēlā me kēia pule a i kēlā me kēia lā.