A 2023 Qhia Rau Epithalon

Kev tshawb fawb qhia tau tias Epitalon, feem ntau sau Epithalone, yog ib qho hluavtaws analogue ntawm Epithalamin, polypeptide ua nyob rau hauv lub caj pas pineal. Yog tias koj xav kawm ntxiv txog qhov peptide no, nyeem tawm 2023 phau ntawv qhia rau Epitalon peptide.

Xibfwb Vladimir Khavinson ntawm Russia tau ua thawj qhov kev tshawb pom ntawm Epitalon peptide ntau xyoo dhau los [i]. Nws tau sim cov nas rau 35 xyoo kom paub ntau ntxiv txog Epitalon muaj nuj nqi.

Kev tshawb fawb qhia tias Epitalon lub luag haujlwm tseem ceeb yog txhawm rau txhawb cov qib endogenous ntawm telomerase. Telomerase yog ib qho endogenous enzyme uas pab txhawb lub cellular replication ntawm telomeres, DNA endcaps. Cov txheej txheem no, nyob rau hauv lem, txhawb nqa DNA replication, uas yog tsim nyog rau kev tsim cov hlwb tshiab thiab rov ua dua tshiab ntawm cov laus, raws li ib txoj kev tshawb nrhiav pom.

Kev tshawb fawb qhia tias telomerase ntau dua hauv cov nas me piv rau cov tsiaj laus. Lawv kuj tsim ntev telomeres, uas txhim kho cellular noj qab haus huv thiab replication.

Kev tsim cov telomerase poob qis nrog lub hnub nyoog hauv cov nas, uas ua rau qeeb ntawm tes sib npaug. Nov yog thaum Epitalon los ua ke, raws li qhia los ntawm kev tshawb fawb soj ntsuam.

Epitalon ua haujlwm li cas?

Epitalon ua haujlwm li cas? Cov kev tshawb fawb tsiaj tau pom tias nws qhov ua tau zoo hauv kev txo qis metabolic, nce hypothalamic rhiab heev, tswj kev ua haujlwm sab hauv pituitary, thiab tswj cov qib melatonin.

Kev tshawb fawb qhia tias DNA nyob rau hauv lub nucleus ntawm txhua lub cell yog ob-stranded; yog li txhua tus tsiaj nrog ib qho Epithalon peptide [ii] yog qhov txawv ntawm caj ces. Telomeres tuaj yeem pom ntawm qhov kawg ntawm DNA strands. Lawv khaws cov DNA ua kom muaj kev ncaj ncees los ntawm kev tawm tsam qhov luv ntawm chromosomes nrog txhua qhov kev faib tawm ntawm tes, raws li kev tshawb fawb soj ntsuam.

Kev tshawb fawb pom tau hais tias cov telomeres ntawm txhua lub cell ua luv dua vim qhov kev rov ua tsis zoo uas tshwm sim txhua zaus cov hlwb sib faib. 

Ntau qhov kev tshawb fawb tau txuas qhov luv luv no rau ntau yam mob uas muaj hnub nyoog, suav nrog kab mob plawv thiab txawm tias tuag ntxov ntxov hauv cov nas.

Raws li kev tshawb fawb tshawb pom, qhov siab ntawm Epitalon tau raug hu ua "tus ciav ntawm cov hluas" vim tias nws muaj kev cuam tshuam zoo rau kev noj qab haus huv thiab kev ua neej.

Cov txiaj ntsig ntawm kev siv Epitalon

Epitalon yog ib yam tshuaj uas, raws li ntau txoj kev tshawb fawb [iii] ua rau cov tsiaj thiab nas, yog lub cev zoo ib yam li qhov tsim los ntawm lub cev nas. Cov txheej txheem no rov pib dua lub moos roj ntsha cellular, tso cai rau cov ntaub so ntswg puas los kho thiab rov ua haujlwm ntawm lub cev.

Ntau xyoo dhau los, cov kws tshawb fawb hauv tebchaws Russia tau ua ntau qhov kev tshawb pom ntsig txog Epithalon. Piv txwv li, cov kws tshawb fawb tau tshawb pom tias nws tuaj yeem rov tsim cov cellular telomerase. Tsis tas li ntawd, lawv nkag siab tias nws tuaj yeem kho lub cev tag nrho thiab txhim kho kev noj qab haus huv. Lawv pom tias nws tuaj yeem thim rov qab kev laus los ntawm kev tsom nws cov hauv paus hauv kev tshawb fawb kev tshawb fawb.

Epitalon Peptide qhov zoo

Kev tshawb fawb qhia tias Epitalon muaj ntau yam zoo. Cov txiaj ntsig zoo ntawm kev noj qab haus huv uas tau pom hauv kev tshawb fawb tsiaj siv Epitalon peptide yog raws li hauv qab no:

  • Lengthes life expectancy ntawm nas.
  • Pab kom tsiaj tsis txhob degenerative mob, xws li Alzheimer's, kab mob plawv, thiab mob qog noj ntshav
  • Ua kom tsaug zog zoo.
  • Txhim kho daim tawv nqaij noj qab haus huv
  • Cov teebmeem ntawm cov leeg nqaij muaj zog
  • Nce tus nqi rov qab
  • Txo lipid peroxidation thiab ROS ntau lawm
  • Nce qhov pib rau kev ntxhov siab
  • Khaws cov tshuaj melatonin tsis tu ncua hauv cov nas

Kev kawm ntxiv ntawm cov protein no yuav tsum tau kawm kom paub txog nws cov teebmeem tag nrho. Los ntawm cov kws tshawb fawb tau kawm txog Epithalon, txawm li cas los xij, zoo li sai sai no nws yuav siv tau los kho thiab kho ntau yam teeb meem kev noj qab haus huv. Qhov zoo tshaj plaws, cov kws tshawb fawb muaj kev cia siab rau Epitalon lub peev xwm ua kev kho mob qog noj ntshav thiab tiv thaiv.

Ntawm no, peb yuav tshuaj xyuas Epitalon peptide qhov ua tau zoo thiab kev siv hluav taws xob ntxiv kom paub meej ntxiv kom koj tuaj yeem txiav txim siab seb puas suav nrog hauv koj cov kev tshawb fawb tshawb fawb.

Efficient Anti-Aging Properties ntawm Epitalon

Biopeptide Epitalon tau pom tias txuas ntxiv lub neej ntawm nas los ntawm 25% hauv kev tshawb fawb hu ua "Lub neuroendocrine txoj kev xav ntawm kev laus thiab kev mob degenerative," sau los ntawm xibfwb Vladimir Dilmice thiab Dr. Ward Dean hauv 1992.

Ntau qhov kev tshawb nrhiav los ntawm Thawj Tswj Hwm St. Petersburg lub koom haum ntawm Bio-kev tswj hwm thiab tus xibfwb Vladimir Khavinson tau lees paub cov txiaj ntsig thawj zaug no.

Epitalon lub peev xwm los tsim cov kev sib txuas ntawm peptide ntawm ntau cov amino acids, raws li pom los ntawm cov kws tshawb fawb no, pab txhawb rau kev sib xyaw ua ke ntawm kev ua haujlwm ntev-ntev. Raws li kev tshawb fawb tshawb pom, nws kuj tseem tuaj yeem cuam tshuam cov qog loj hlob thiab ua kom lub hlwb ua haujlwm.

Khavinson pom, nyob rau hauv cov nas, uas biopeptides ua rau kom lub cev muaj zog thiab txo qis kev tuag los ntawm yuav luag 50% tom qab 15 xyoo ntawm kev soj ntsuam.

Nws kuj tau muab pov thawj tias kev sib cuam tshuam ntawm Epithalon biopeptides thiab DNA tuaj yeem tswj hwm cov kev ua ub no tseem ceeb, ua kom muaj sia nyob ntev.

Cov kev tshawb fawb qhia tias Epitalon txuas ntxiv lub neej ntawm cov nas piv rau cov tsiaj uas siv cov placebo los ntawm lub hnub nyoog peb lub hlis mus txog thaum tuag. Raws li kev tshawb fawb tau tshwm sim, chromosomal aberrations nyob rau hauv cov pob txha pob txha hlwb tau zoo sib xws tom qab kev kho mob nrog Epitalon. Cov nas uas tau kho nrog Epitalon kuj tsis pom muaj cov tsos mob ntawm tus kab mob leukemia. Txoj kev tshawb nrhiav qhov kev tshawb pom, suav tag nrho, qhia tias peptide no muaj qhov cuam tshuam rau kev laus thiab yuav siv tau yam nyab xeeb yam tsis muaj hnub kawg.

Ntau qhov kev tshawb fawb tsiaj tau lees paub cov kev mob tshwm sim hauv qab no ntawm Epitalon:

  • Cortisol thiab melatonin synthesis qeeb nrog lub hnub nyoog ntawm cov liab, uas pab tswj lub cortisol tsis tu ncua.
  • Cov nas 'cov txheej txheem ua me nyuam raug tiv thaiv los ntawm kev puas tsuaj, thiab kev puas tsuaj raug kho.
  • Cov qauv retinal tseem nyob tsis zoo txawm hais tias tus kab mob tau nce hauv retinitis pigmentosa.
  • Cov nas uas muaj mob qog noj ntshav tau ntsib kev loj hlob qeeb.

Kev cuam tshuam rau ntawm daim tawv nqaij 

Cov kev tshawb fawb tsiaj tau qhia tias ntxiv rau nws cov khoom tiv thaiv kev laus, Epitalon kuj tseem txhim kho daim tawv nqaij noj qab haus huv.

Raws li Dr. Khavinson txoj kev tshawb fawb, Epithalon tuaj yeem txhawb cov hlwb [iv] uas yog tus saib xyuas kho thiab tswj cov kab mob extracellular matrix uas tswj cov tawv nqaij noj qab haus huv thiab hluas. Collagen thiab elastin yog ob tug anti-aging superstars nyob rau hauv lub extracellular matrix.

Cov kev tshawb fawb pom tau tias ntau yam tshuaj tiv thaiv kev laus cog lus tias yuav tiv thaiv collagen hauv daim tawv nqaij, tab sis tsuas yog Epitalon ua li ntawd. Epithalon nkag mus rau hauv cov hlwb thiab txhawb kev nthuav dav thiab loj hlob ntawm fibroblasts lub luag haujlwm tsim collagen thiab lwm cov proteins. Yog li ntawd, qhov no txhawb kev noj qab haus huv ntawm daim tawv nqaij, raws li kev tshawb fawb pom.

Cov kev sim qhia tau hais tias, txawm li cas los xij, Epithalon peptide muaj txiaj ntsig tiv thaiv kev laus dhau qhov ua tau raws li qhov muag. Kab mob, kab mob, thiab kev raug mob yog txhua yam uas nws muaj peev xwm tiv thaiv tau. Cov tawv nqaij laus dhau los ua qhuav, tsis muaj zog, thiab ntau dua los tsim kua muag. Raws li kev sim tshuaj pom, kev siv Epitalon rau ntawm daim tawv nqaij yuav tiv thaiv tau cov kev mob tshwm sim.

Kev kho mob ntawm Retinitis Pigmentosa 

Cov pas nrig hauv retina raug rhuav tshem los ntawm cov kab mob degenerative hu ua retinitis pigmentosa. Thaum lub teeb hits lub retina, nws ua rau tso tawm cov lus tshuaj los ntawm cov pas nrig. Epitalon tau pom tias yuav txo qis kev puas tsuaj rau lub retina los ntawm qhov tsis sib xws hauv kev tshawb fawb soj ntsuam.

Epitalon txhim kho cov retinal muaj nuj nqi hauv kev ntsuam xyuas nas los ntawm kev txwv cov cell degeneration thiab tswj cov qauv pas nrig, raws li kev tshawb fawb tshawb fawb.

Kev tshawb fawb qhia tias Epitalon yog kev kho mob zoo rau retinitis pigmentosa hauv kev tshawb fawb nrog nas thiab nas. Txawm li cas los xij, yuav tsum tau kawm ntxiv los txheeb xyuas cov txiaj ntsig no. Ntawm no koj ua tau yuav peptides online.

[i] Anisimov, Vladimir N., thiab Vladimir Kh. Khavinson. "Peptide Bioregulation of Aging: Cov txiaj ntsig thiab kev cia siab." Biogerontology 11, nr. 2 (Lub Kaum Hli 15, 2009): 139–149. doi:10.1007/s10522-009-9249-8.

[ii] Frolov, DS, DA Sibarov, and AB Vol'nova. "Kev hloov pauv hloov hluav taws xob tau pom hauv nas lub cev muaj zog Neocortex tom qab Intranasal Epitalon Infusions." PsycEXTRA Dataset (2004). doi: 10.1037/e516032012-081.

[iii] Khavinson, V., Diomede, F., Mironova, E., Linkova, N., Trofimova, S., Trubiani, O., … Sinjari, B. (2020). AEDG Peptide (Epitalon) Stimulates Gene Expression thiab Protein Synthesis thaum Neurogenesis: Muaj peev xwm Epigenetic Mechanism. Molecules, 25(3), 609. doi: 10.3390 / molecules 25030609

[iv] Chalisova, NI, NS Linkova, AN Zhekalov, AO Orlova, GA Ryzhak, and V. Kh. Khavinson. "Short Peptides Stimulate Cell Regeneration nyob rau hauv daim tawv nqaij thaum laus." Kev nce qib hauv Gerontology 5, no. 3 (Lub Xya Hli 2015): 176–179. doi: 10.1134 / s2079057015030054.

[v] Korkushko, OV, V. Kh. Khavinson, VB Shatilo, thiab LV Magdich. "Qhov cuam tshuam ntawm Peptide Kev Npaj Epithalamin ntawm Circadian Rhythm ntawm Epiphyseal Melatonin-Producing Function hauv Cov Neeg Laus." Daim ntawv tshaj tawm ntawm Kev Tshawb Fawb Biology thiab Tshuaj 137, No. 4 (Lub Plaub Hlis 2004): 389–391. doi: 10.1023/b:wb.0000035139.31138.bf.

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