Research shows that Epitalon, often spelled Epithalone, is a synthetic analog of Epithalamin, a polypeptide produced in the pineal gland. If you are interested in learning more about this peptide, keep reading out the 2023 guide to Epitalon peptide.
Professor Vladimir Khavinson of Russia made the first discovery of the Epitalon peptide many years ago[i]. He experimented on mice for 35 years to learn more about Epitalon function.
Research shows that Epitalon’s primary function is to boost endogenous levels of telomerase. Telomerase is an endogenous enzyme that facilitates the cellular replication of telomeres, the DNA endcaps. This process, in turn, encourages DNA replication, which is necessary for developing new cells and the renewal of older ones, as per study findings.
Research suggests that telomerase production is higher in younger mice compared to older animals. They also create longer telomeres, which improve cellular health and replication.
Production of telomerase declines with age in mice, which slows down cell multiplication. Here’s when Epitalon comes in handy, as shown by clinical studies.
What function does Epitalon play?
How does Epitalon function? Animal studies have shown its efficacy in moderating metabolic rate, increasing hypothalamic sensitivity, maintaining the anterior pituitary function, and controlling melatonin levels.
Research reveals that the DNA in the nucleus of each cell is double-stranded; hence each creature with an Epithalon peptide[ii] is genetically distinct. Telomeres may be found at the very end of DNA strands. They preserve DNA sequence integrity by counteracting the shortening of chromosomes with each cell division, as per clinical findings.
Research implies that the telomeres of each cell become shorter because of the imperfect replication that occurs every time cells divide.
Several studies have linked this shortening to various age-related illnesses, including cardiovascular disease and even premature death in mice.
According to research findings, a high concentration of Epitalon has been called the “fountain of youth” because of its positive impact on health and lifespan.
Outcomes of Using Epitalon
Epitalon is a chemical that, according to several studies[iii] performed on animals and mice, is physiologically similar to the one generated by the mouse body. This process resets the cellular biological clock, allowing damaged tissues to heal and restore normal organ function.
Over the last several years, scientists in Russia have made many discoveries related to Epithalon. For instance, scientists have discovered that it can revive cellular telomerase production. In addition, they understand that it may revitalize the body as a whole and improve health. They found that it can even reverse aging by targeting its root cause in research studies.
Epitalon Peptide’s Advantages
Studies show that Epitalon has several advantages. The positive benefits on health that have been seen in animal studies using Epitalon peptide are as follows:
- Lengthens life expectancy of mice.
- Helps keep animals free from degenerative conditions, including Alzheimer’s, heart disease, and cancer
- Increases the quality of sleep.
- Enhanced skin health
- Effects on muscle cell strength
- Increases the rate of recovery
- Decreases lipid peroxidation and ROS production
- Raising the threshold for emotional stress
- Maintains steady amounts of melatonin in mice
More study of this protein is required to learn its full effects. From what researchers have learned about Epithalon, however, it seems that it will soon be accessible to treat and cure many health problems. Quite remarkably, researchers have high hopes for Epitalon’s potential as a cancer therapy and prevention.
Here, we’ll examine Epitalon peptide’s efficacy and utility in further detail so you can decide whether to include it in your research studies.
Efficient Anti-Aging Properties of the Epitalon
Biopeptide Epitalon was shown to extend the lives of rats by 25% in a study titled “The neuroendocrine theory of aging and degenerative illness,” written by Professor Vladimir Dilmice and Dr. Ward Dean in 1992.
Multiple follow-up investigations by President St. Petersburg Institute of Bio-regulation and Professor Vladimir Khavinson validated these initial results.
Epitalon’s capacity to form peptide connections between many amino acids, as found by these scientists, contributes to the compound’s longevity-extending effects. According to research findings, it may also inhibit tumor growth and increase brain activity.
Khavinson found, in mice, that biopeptides dramatically enhanced physiological function and lowered mortality by almost 50% after 15 years of clinical monitoring.
He also provided evidence that interactions between Epithalon biopeptides and DNA might regulate essential genetic activities, effectively extending lifespan.
Studies show that Epitalon extended the lives of mice compared to placebo-treated animals from the age of three months till death. According to study results, chromosomal aberrations in bone marrow cells were similarly reduced after treatment with Epitalon. Mice treated with Epitalon also showed no signs of developing leukemia. The study’s findings, taken as a whole, indicate that this peptide has a significant anti-aging impact and may be used safely indefinitely.
Several animal studies confirm the following side effects of Epitalon:
- Cortisol and melatonin synthesis slows with age in monkeys, which helps maintain a steady cortisol rhythm.
- Rats’ reproductive systems were shielded from harm, and impairments were repaired.
- The retinal structure remains intact despite the disease’s progression in retinitis pigmentosa.
- Rats with colon cancers experienced a growth slowdown.
Impact on Skin
Animal studies have revealed that in addition to its anti-aging properties, Epitalon also improves skin health.
According to Dr. Khavinson’s research, Epithalon may stimulate the cells[iv] that are in charge of repairing and maintaining the extracellular matrix that maintains skin healthy and young. Collagen and elastin are two anti-aging superstars in the extracellular matrix.
Studies show that multiple anti-aging lotions promise to fortify collagen in the skin, but only Epitalon does so. Epithalon enters the cells and stimulates the expansion and maturation of the fibroblasts responsible for producing collagen and other proteins. Consequently, this promotes healthy skin renewal, according to research findings.
Experiments show that, however, Epithalon peptide is effective against the effects of aging beyond what meets the eye. Disease, infection, and injury are all things it can protect against. Older skin becomes dry, fragile, and more prone to tearing. As clinical trials show, applying Epitalon to the skin may prevent such side effects.
Treatment of Retinitis Pigmentosa
Rods in the retina are destroyed by the degenerative illness known as retinitis pigmentosa. When light hits the retina, it triggers the release of chemical messages through rods. Epitalon was shown to reduce the degenerative damage to the retina caused by the disorder in a clinical investigation.
Epitalon improves retinal function in rodent tests by halting cell degeneration and maintaining rod structure, as per research studies.
Research suggests that Epitalon is a successful therapy for retinitis pigmentosa in research involving mice and rats. However, further study is required to verify these results. Here you can buy peptides online.
[i] Anisimov, Vladimir N., and Vladimir Kh. Khavinson. “Peptide Bioregulation of Aging: Results and Prospects.” Biogerontology 11, no. 2 (October 15, 2009): 139–149. doi:10.1007/s10522-009-9249-8.
[ii] Frolov, D. S., D. A. Sibarov, and A. B. Vol’nova. “Altered Spontaneous Electric Activity Detected in Rat Motor Neocortex after Intranasal Epitalon Infusions.” PsycEXTRA Dataset (2004). doi:10.1037/e516032012-081.
[iii] Khavinson, V., Diomede, F., Mironova, E., Linkova, N., Trofimova, S., Trubiani, O., … Sinjari, B. (2020). AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism. Molecules, 25(3), 609. doi:10.3390/molecules25030609
[iv] Chalisova, N. I., N. S. Linkova, A. N. Zhekalov, A. O. Orlova, G. A. Ryzhak, and V. Kh. Khavinson. “Short Peptides Stimulate Cell Regeneration in Skin During Aging.” Advances in Gerontology 5, no. 3 (July 2015): 176–179. doi:10.1134/s2079057015030054.
[v] Korkushko, O. V., V. Kh. Khavinson, V. B. Shatilo, and L. V. Magdich. “Effect of Peptide Preparation Epithalamin on Circadian Rhythm of Epiphyseal Melatonin-Producing Function in Elderly People.” Bulletin of Experimental Biology and Medicine 137, no. 4 (April 2004): 389–391. doi:10.1023/b:bebm.0000035139.31138.bf.