Udliwanondlebe luka-Alzheimer's kwiRadio iMemTrax: Ukufumana uBuqu ngeDementia-Icandelo 2
Kwiveki ephelileyo, kweyethu blog iposti, saqala udliwanondlebe lwethu lwe-Alzheimer's Speaks Radio kunye nentshayelelo kuGqr. Ashford, umqambi we Uvavanyo lweMemTrax, kunye nesishwankathelo sikaLori La Bey kunye nembali yakhe yokujongana neDementia. Kule veki mna noGqr. Ashford sixoxa ngoTatomkhulu wethu owayenesifo sika-Alzheimer size sabelane ngokuba kwakunjani ukuva esi sifo siyingozi. Kule veki siza kukhuphela ngakumbi udliwano-ndlebe kwaye sinike ulwazi oluluncedo ukunceda ukukhuthaza uphando lwesifo sika-Alzheimer kunye nokwazisa.
Icandelo 2 : Ukuphonononga uVavanyo lweMemTrax kunye nokuBanzi kweDementia
ULori:
Phambi kokuba singene kumgca wethu wemibuzo ndifuna ukwazisa uCurtis Ashford, endikholelwa ukuba ngunyana wakho, kwaye waba nomdla kuvavanyo lwengqondo njengomfundi onesidanga sokuqala kwiYunivesithi yaseCalifornia State eSan Jose (eSilicon Valley) apho waphumelela khona ngo-2011 Kule minyaka mi-3 idlulileyo usebenze ngokusondeleyo ukuphuhlisa lo msebenzi wokuhlola olula ukuvavanya utshintsho kwimemori usebenzisa imidiya yoluntu, ikhompyutha, kunye nobuchwepheshe be-intanethi ukwazisa nokukhuthaza ukuhlolwa kweememori rhoqo kunye nokungaguqukiyo. UCurtis unomdla wokukhuthaza ukufunyanwa kwangoko kotshintsho lwenkumbulo olunokuthi lube luphawu lokuqala kwesifo i-Alzheimer okanye ubukho bezinye izizathu zokuphazamiseka kwengqondo. Ngoku ukhokela iMemTrax ekuphuhliseni i Uvavanyo lwengqondo isoftware enovakalelo lokuvavanya eyona nguquko yokuqala yenkumbulo kunye nokukhuthaza ungenelelo lwangethuba phambi kokuba ukhubazeko lophuhliso lwengqondo luphuhle. Wamkelekile uCurtis, unjani namhlanje?
UCurtis:
Molo Lori, enkosi kakhulu ngokuba nathi namhlanje!
ULori:
Ewe ndichulumancile, ndivile malunga nenkampani yakho malunga nonyaka ngoku kwaye enye yezinto endifuna ukunibuza yona nobabini, ndiza kuqala ngoCurtis apha. Ngaba ukhe wachukunyiswa buqu kusapho lwakho okanye umhlobo osondeleyo onesifo sengqondo esiyingozi, abaphulaphuli bethu bahlala bethanda ukuva ukuba kukho isuntswana lobuqu.
UCurtis:
Ewe, utatomkhulu wam eneneni, utatomkhulu wam uJohn wayenento embi kakhulu. Ndandiselula kakhulu, malunga neminyaka eli-14 okanye eli-15 ubudala, njengoko waqalisa ukuwohloka. Bendikhe ndihlale naye, bekubuhlungu nyani kuba qho xa ubuyela endwendwe ebekhe alibale kancinci ngawe okanye ngotata okanye alibale nje igama lomntu. Ngokuqinisekileyo unokuyichola ixesha ngalinye kwaye uyazi ukuba kukho into eyenzekayo.
ULori:
Mmmh, ewe. UGqr. Ashford, kunjani kuwe, yayingutata wakho wayenesifo sengqondo esiyingozi okanye wayekwelinye icala?
UGqr. Ashford:
Hayi, ngutata wam lowo.
Umdla wam kule nto ngokwenene wawuvela kwicala elahlukileyo, xa ndiseBerkeley umdla wam ngaphandle kwayo yonke ipolitiki yayizama ukuphila ngonaphakade ngoko ndandinomdla kakhulu kwinkqubo yokuguga, kunye nendlela yokuyiyeka. Njengoko ndandiyifunda ngakumbi ndaqalisa ukujonga ubuchopho njengelungu elilawula yonke into, yaye ndacinga ukuba ukuze ndiyiqonde inkqubo yokwaluphala kwakuza kufuneka ndiqonde indlela ingqondo ekulawula ngayo ukwaluphala. Njengoko ixesha lalihamba ndaqonda ukuba andizukwazi ukunqanda inkqubo yokwaluphala, kwakuza kufuneka ndiphile obona bomi bubhetele ndandinokubuphila. Ndandisenomdla kwiindlela zokuguga kwaye kwavela ukuba xa ndijonga abantu kunye ne-baby boomers, endililungu labo, ukuguga, zininzi izinto esinokuzenza ukunqanda ukufa; singatshayi imidiza, siphile ubomi obusempilweni, sinxibe amabhanti ezihlalo zethu, kwaye sibaleke iingxaki ezininzi ezinokukubangela ukuba ufe. Kodwa kwathi ke, ndakuzifunda ngakumbi nangakumbi izinto, eyona ngxaki inzima endayibonayo xa ndijonge phambili yayisisifo sika-Alzheimer, yaye njengoko abantwana abakhula bekhula yaye bezinyamekela ngakumbi yaye bephila ixesha elide nangaphezulu ingxaki yesifo sika-Alzheimer iya kuba sisimo esidala. eyona ngxaki inkulu kule nkulungwane.
Ngoko ndaba nomdla kwisifo sika-Alzheimer ngokwembono yezeMpilo yoLuntu. Ngo-1978, ndaba ngumhlali wokuqala oyintloko kwicandelo labagula ngengqondo e-UCLA kwaye ndaqala ukubona ukuba malunga ne-2 kuzo zonke izigulana ezi-5 esavuma ukuba azikhumbuli nto. Ndandibacela ukuba bakhumbule amagama ama-5 kwaye ngokucacileyo nabani na onokuwakhumbula la magama alula, ndandibuya ndize ndithi ngawaphi amagama endikucele ukuba uwakhumbule? Emva koko abantu aba-2 kwaba-5 babengakhumbuli nokuba ndibacele ukuba bakhumbule amagama ama-5, yaye ndandingathi, “ayinangqondo le nto.” Ndandisele ndinomdla kakhulu kwinkumbulo, umcebisi wam yayinguNjingalwazi uLissy Jarvik, owayefunda ngesifo sika-Alzheimer. Ngoko sacinga ngale ngxaki. Ngokucacileyo besicinga ukuba isifo sika-Alzheimer sixhaphake kakhulu kunokuba wonke umntu ebecinga, kwaye kungcono siqale ukuba nomdla kwinto ekufuneka siyenzile ngaso. Siye safunda ezinye zeziphumo zokuqala zenzululwazi ezisandula ukuphuma ezichonge iindlela ezithile zobuchopho ezichatshazelwe sisifo sika-Alzheimer esibandakanya umchiza obizwa ngokuba yi-Acetyl-choline. Ngoko siye safumanisa indlela yokuzama ukunyusa inani le-Acetyl-choline kwingqondo kwaye oko kusikhokelela ekusebenziseni iyeza elibizwa ngokuba yi-physostigmine elichiza elifana neziyobisi zangoku ezisetyenziselwa ukunyanga isifo se-Alzheimer, njenge-donepezil (i-Aricept) okanye i-galantamine ( I-Razadyne), okanye i-rivastigmine (i-Excelon kunye ne-Excel patch). Sawenza loo msebenzi ngo-1978-1979 saze sawupapasha ngo-1981 ngoko ke yayingumbono wokuzama ukunyanga izigulana ezinesi sifo, kwaye kwakukho ukufana okusondeleyo nokusetyenziswa kweli chiza kunye nalawo asetyenziselwa i-Parkinson.
Into endakhawuleza ndayiqonda kukuba la mayeza akasinqandi isifo sika-Alzheimer abonakala esinceda kancinane, kodwa awasinqandi. Sidinga ngokwenene ukuqonda isifo ukuze sikwazi ukumisa inkqubo yesifo ngokupheleleyo, kwaye ndisakholelwa ukuba oko kunokwenzeka, kwaye ukuba sinokuhla ngendlela efanelekileyo yophando ndiyakholelwa ukuba sinokusiphelisa ngokupheleleyo isifo sika-Alzheimer, kodwa siya kuthatha ukuqonda. ukuba yintoni inkqubo. Kulapho ndaya ekuphuhliseni ithiyori ye-neuroplasticity kunye nendlela i-neuroplasticity ehlaselwa ngayo kwingqondo yi-Alzheimer pathology. Kwakukho nje iphepha elaphuma kwiJenali ebizwa ngokuba “Ukuguga,” ngoSeptemba 2014, ngomnye wabahlobo bam, uDale Bredesen, oqhuba iBuck Institute on Aging eMntla California, kwaye unephepha elinesihloko esithi “Reversal of Cognitive Decline. , Inkqubo yeNovel Therapeutic,” kwaye usebenzisa ithiyori endayiphuhlisayo ngo-2002, yokuba ukuba uyaziqonda iindlela ezichanekileyo i-Alzheimer's ehlasela ngayo ingqondo unokutshintsha izinto ezininzi ezahlukeneyo ekutyeni kwakho nakwindawo enokuthi iyeke. le nkqubo ngokupheleleyo. Le yeyona nto sifuna ukuyenza, asifuni ukuba abantu banyangelwe i-Alzheimer's, sifuna ukuba ithintelwe. Ndiyavuya ukuthetha nawe ngakumbi malunga naloo nto.
ULori:
Kulungile. Kulungile, kuyamangalisa, ndiyazi ukuba i-Alzheimer's Disease International isanda kuphuma nengxelo enkulu malunga nokunciphisa umngcipheko endimaziyo uMart Wortman, uMlawuli oyiNtloko, wayechane kakhulu ukuba oku kwakungesosiqinisekiso. Uyazi zonke ezi zinto bazikhankanyayo zilungile kumzimba wethu xa uwonke kodwa ngokuqinisekileyo njengoko i-heck ayinakukhathaza ukwenza izinto ngakumbi malunga nokuqhubela phambili izinto.