Kutsimikizika kwa MemTrax Kuyesedwa kwa Memory Kuyerekeza ndi Montreal Cognitive Assessment mu Kuzindikira Kuwonongeka Kwachidziwitso Chochepa ndi Dementia chifukwa cha Matenda a Alzheimer mu Gulu la China

 

Xiaolei Liu, Xinjie Chen , Xianbo Zhou , Yajun Shang, Fan Xu , Junyan Zhang, Jingfang He, Feng Zhao, Bo Du, Xuan Wang, Qi Zhang, Weishan Zhang, Michael F Bergeron, Tao Ding, J Wesson Ashford, Lianmei Zhong

• PMID: 33646151
• DOI: 10.3233/JAD-200936

Kudalirika

 

Background: Chidziwitso cha digito chovomerezeka, chodalirika, chofikirika, chosangalatsa komanso chotsika mtengo chophimba chida kuti agwiritsidwe ntchito kuchipatala akufunika mwachangu.

 

Cholinga: Kuti fufuzani zachipatala za MemTrax MemTrax Memory Memory kuti muzindikire mwamsanga kuwonongeka kwa chidziwitso m'gulu lachi China.

 

Njira: MemTrax ya mphindi 2.5 ndi Montreal Kuwunika Mwachidziwitso (MoCA) adachitidwa ndi anthu 50 omwe adapezeka kuti ndi odziwika bwino (CON), 50 kulephera kuzindikira pang'ono chifukwa cha AD (MCI-AD), ndi odzipereka odzipereka a 50 Alzheimer's (AD). Maperesenti a mayankho olondola (MTx-% C), nthawi yoyankhira (MTx-RT), ndi ziwerengero zophatikiza (MTx-Cp) za MemTrax ndi zigoli za MoCA zidawunikidwa mofananiza ndi ma curve a wolandila (ROC) adapangidwa.

 

Results: Kusanthula kwa mizere yosinthika kwamitundu yambiri kukuwonetsa MTx-% C, MTx-Cp, ndi mphambu ya MoCA zinali zotsika kwambiri mu MCI-AD motsutsana ndi CON komanso mu AD motsutsana ndi magulu a MCI-AD (onse okhala ndi p≤0.001). Pakusiyanitsa kwa MCI-AD kuchokera ku CON, kukhathamiritsa kwa MTx-% C kwa 81% kunali ndi 72% kukhudzika ndi 84% kutsimikizika ndi dera lomwe lili pansi pa curve (AUC) ya 0.839, pomwe gawo la MoCA la 23 linali ndi 54% kukhudzika. ndi 86% yeniyeni yokhala ndi AUC ya 0.740. Pakusiyanitsa kwa AD kuchokera ku MCI-AD, MTx-Cp ya 43.0 inali ndi 70% sensitivity ndi 82% yeniyeni ndi AUC ya 0.799, pomwe ma MoCA 20 anali ndi 84% sensitivity ndi 62% mwachindunji ndi AUC ya 0.767.

 

Kutsiliza: MemTrax imatha kuzindikira bwino onse omwe adapezeka ndi matenda a MCI ndi AD molondola bwino poyerekeza ndi MoCA yotengera ma AUC mgulu lachi China. Kutsimikizika kwa MemTrax Memory Test kwakhazikitsidwa.

 

Keywords: Matenda a Alzheimer's; chida chowunikira mwachidziwitso; kupitiriza kuzindikira ntchito paradigm; kuwonongeka kwachidziwitso pang'ono.